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In asexual populations, both clonal interference, competition for fixation among concurrent beneficial mutations, and genetic drift, waste of beneficial mutations purely by random events, limit the speed of adaptation. In sexual population, on the other hand, loss of beneficial mutations due to clonal interference can be alleviated by genetic recombination. By considering the simplest two-locus model with an infinite number of sites each, we study quantitatively how much the speed of adaptation can be enhanced by genetic recombination. We first consider the infinite population size limit which renders the population dynamics deterministic and tractable analytically to a certain extent. Having a hint from the deterministic dynamics, we investigate the finite population dynamics using numerical simulations.

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Su-Chan Park , Catholic University of Korea
Institute for Genetics, Zülpicher Str. 47a, Seminar Room, 4th floor
Contact: not specified