| February 02, 16:00
Germline fitness based scoring of cancer mutations
The effects of mutations in cancer can be analyzed with respect to the evolutionary conservation of the genomic target. I will briefly discuss, how to use Kimura's one locus model to infer fitness effects of mutations in a controlled manner and how to asses the significance of such scoring schemes when it comes to understand cancer evolution.
Andrej Fischer, Institut für Theoretische Physik, Universität Köln
Seminarraum Theoretische Physik
Contact: not specified