| February 02, 16:00
Germline fitness based scoring of cancer mutations
The effects of mutations in cancer can be analyzed with respect to the evolutionary conservation of the genomic target. I will briefly discuss, how to use Kimura's one locus model to infer fitness effects of mutations in a controlled manner and how to asses the significance of such scoring schemes when it comes to understand cancer evolution.
Institut für Theoretische Physik, Universität Köln
Seminarraum Theoretische Physik
Contact: not specified