Thesis Defense | November 05, 11:00

Different modes of spatial tumor growth under neutral evolution


The genetic heterogeneity found within a tumor also extends to the spatial dimension of clonal architecture, but only recently has high-depth multi-region sequencing data become available. We use spatially resolved genetic data to study a tumor’s mode of evolution and growth as well as population genetic theory of mutant type extinction to infer cancer cell turnover rates and mutation rates.


Arman Angaji, IBP, Berg group
https://uni-koeln.zoom.us/j/9435227210
Contact: not specified